Monday, August 23, 2021

Ram It Through

 Not Consulted,


  The "more fortunate" countries of the world made the kind of deal with Pfizer last fall, that you or I might make with a mortgage lender, or when taking out a home-equity loan. The superior party bears no risk, and actually gains even more if the lesser party defaults. No way out, except to pay up.
  Pfizer had good reason to exact such iron-clad contracts, which held Pfizer blameless in any circumstance which might arise. It's good-business, of course, but the risks for antibody dependent enhancement (of viral pathogenicity) were well known, and no coronavirus vaccine studied had been successful in 20 years of trying. 
The vaccinated animals made antibodies, but died at higher rates than the unvaccinated animals when challenged with viral infection.
  Antibodies "against" a virus can turn out to be "for" the virus, to help it be more infectious. 
That effect takes time to develop, like half a year to get started, in general.
  There is evidence that is happening with vaccines against the original "alpha"-COVID spike protein now helping the Indian-originated delta-COVID have enhanced infectivity in vaccinated people.
  That is just getting started, though, because it's kind of accidental that delta-COVID can do a bit of this. Delta-COVID evolved in India with about 4% population vaccination, so it was just trying to spread effectively in a population. It did not have to dodge vaccine-created antibodies on the path to that success.
  Now, in much of the world, like where we live, a majority of susceptible people have blocking-and-enhancing antibodies to alpha-COVID spike protein, due to vaccination. The viral mutations of resistance to blocking antibodies will be rewarded with more viral success in spread, but there is now a new option. Viral mutation to get more TURBO-BOOST out of the enhancing antibodies opens the door to new viral strains that will be more infectious to the vaccinated than to the unvaccinated. 
This environmental niche has been created among spike-protein-vaccinated human hosts. 
I suspect that mutant COVID variants yet-unnamed are already filling it. 
Stay tuned, especially to Israel.

  A scientific paper from Nature, last October, gives clear historical context regarding this common and devastating and difficult to avoid vaccination side effect.
Look, they got this problem when they tried to make vaccines for SARS-Co-V and MERS, the close cousins of our current COVID family.
​  ​In this Perspective, we summarize examples of vaccine-associated disease enhancement in the history of developing vaccines against respiratory syncytial virus, dengue virus, SARS-CoV and Middle East respiratory syndrome coronavirus, which highlight the importance of a robust safety and efficacy profile, and present recommendations for preclinical and clinical evaluation of COVID-19 vaccine candidates as well as for vaccine design and optimization.

​  Here is a specific mechanism of vaccine-antibodies to alpha-COVID spike protein enhancing the ability of delta-COVID to enter human cells, once the spike protein anchors to the cell.​ This is demonstrated to predominate in effet over the blocking antibodies, since delta mutated and they lost effectiveness against it.
Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?
​  ​Using molecular modeling approaches, we show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs. We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains. This stabilizing mechanism may facilitate the conformational change that induces the demasking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain. However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity.

​Pfizer coerced deals upon countries that desired to obtain it's COVID-19 vaccines last year, which broke laws of those countries, could not be revoked under any conditions or in light of new information or treatments (ivermectin, deadly side effects), and in some cases gave Pfizer ownership of things like military bases, should the country default. Thanks Luc. It was a seller's market. Israel got a deal.
​  In history’s largest medical experiment with “vaccines” that have not been approved for use in humans, it is the buyers’ responsibility to defend Pfizer for causing harm, leaked documents showed. Pfizer has escaped all liability and is indemnified, arguing that side effects and the long-term effects of the injections are unknown – to the company as well. Pfizer thus admits that an insufficiently tested product is being pushed in literally billions of doses on the world market.
  This means that all responsibility for costs, healthcare, etc. due to vaccine damage – no matter how large and onerous – is passed on to the taxpayers in the countries that have signed the agreements. Since the agreements put each country’s own laws out of play, they have all been signed at government level.


(Ram it through quick!)  British Medical Journal:  Covid-19: FDA set to grant full approval to Pfizer vaccine without public discussion of data
​  ​Last year the FDA said it was “committed to use an advisory committee composed of independent experts to ensure deliberations about authorisation or licensure are transparent for the public.”1 But in a statement, the FDA told The BMJ that it did not believe a meeting was necessary ahead of the expected granting of full approval.

​  People have not been able to get doctors to prescribe ivermectin for COVID treatment and prevention, so they have bought veterinary ivermectin to use, mostly the horse-paste, but there are also some horse pills. A horse weighs about 10 times as much as a human, so people who take a horse pill, at 10X the human dose are getting nausea, vomiting, diarrhea and dizziness, but that's all. No deaths, and the one "hospitalization" in Mississippi, does not appear to be confirmed. Take the right dose. If you can't do math, get help from a farm-boy who can. These horse products are used on goats, rabbits, farmers and farmers children, at the correct scaling doses. Ask a farmer with critters.​ FDA resorts to shouting and public shaming, because it's hard to fear safer-than-Tylenol ivermectin.
The FDA Is Begging You Not to Take Horse Dewormer for Covid-19
“You are not a horse. You are not a cow,” the Food and Drug Administration said about using the drug that hosts on Fox News have been pushing


​American Journal of Therapeutics: 
  Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally.

Unvaccinated Scientist
pictured yesterday harvesting Fairy Squash, a winter squash variety



10 comments:

  1. Greetings from Maine, love your perceptions. Quick question. Is US customs allowing Ivermectin from India to enter the country? Kim & Bob

    ReplyDelete
    Replies
    1. Yes, US customs lets in ivermectin and most other pharmaceuticals from India, every day of the week. People tell me it takes under 2 weeks to arrive in the US.

      Delete
    2. Thanks! Keep up the good work, you are a shining star.

      Delete
  2. Been doing the horse paste since June 2020. Haven't had any problems from the paste, nor any symptoms of the coove. My brother and his family contracted and shared Covid over the winter and while I have been in close contact with them throughout the whole time, so far so good.

    Keep us the good work sir, I certainly appreciate your informative and rational writing. Plus, your garden pics are nice to see.

    ReplyDelete
    Replies
    1. I'm glad you have been taking just enough horse paste ivermectin at each dose. The tube lasts much longer that way, lasts a couple of months, or so, and you don't get queasy.
      Good thing those people were not taking huge pills of horse Tylenol!

      Delete
  3. Love the picture. Any tips for a fellow Texan on dealing with squash bugs? They keep decimating my squash plants even after checking.

    ReplyDelete
    Replies
    1. I can get squash in Yoakum, but I can't get squash in Austin. The Fairly squash are a choice I made to try, because they have thinner stems that don't appear to squash borers, but I couldn't get even obscure and resistant squash to grow in Austin.

      Delete
    2. Should be: "don't appeal to squash borers".

      Delete
  4. Could the emergence of Delta in India be due to the 4% jabbed being in large cities therfore providing a "pool" for viral mutation??

    ReplyDelete
    Replies
    1. That seems unlikely to have been enough vaccinated people for enough time to put a trend on viral mutation success. That's just my moderately informed opinion. It could have contributed to one or 2 mutations out of the bunch, but it should not have been a driving factor.

      Delete